Recombinant SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) Antibody
Product Sizes
100 ug
£671.00
6390-MSM8-P1-100UG
About this Product
- SKU:
- 6390-MSM8-P1
- Additional Names:
- Iron-sulfur subunit of complex II
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rSDHB/6948
- Clonality:
- Monoclonal
- Extra Details:
- Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II; a key component of the citric acid cycle and the electron transport chain; a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane.Many cancers are generally positive for SDHB; including renal cell carcinomas and gastrointestinal stromal tumors. A subset of RCC and GIST tumors that are associated with SDH mutations; Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa180-280) of human SDHB protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 32kDa
- Research Area:
- Cardiovascular; Colon Cancer; Mitochondria Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=131816
