SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) Antibody
Product Sizes
100 ug
£671.00
6390-MSM1-P1ABX-100UG
About this Product
- SKU:
- 6390-MSM1-P1ABX
- Additional Names:
- Iron-sulfur subunit of complex II
- Application:
- Western Blot
- translate.label.attr.clone:
- SDHB/2126
- Clonality:
- Monoclonal
- Extra Details:
- Succinate dehydrogenase (SDH) is Complex II in the mitochondria; vital for mitochondrial electron transport; as well as Krebs cycle function.Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA); an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation.Antibody to SDHB is helpful in the identification of phaeochromocytomas; paragangliomas and GIST.
- Host:
- Mouse
- Immunogen:
- Recombinant human SDHB fragment around aa 165-273 (Exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 32kDa
- Research Area:
- Cardiovascular; Colon Cancer; Mitochondria Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=121056
