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Antibodies

Recombinant CD138 / Syndecan-1 (SDC1) (Plasma Cell Marker) Antibody

Product Sizes
20 ug
£364.00
6382-MSM6-P0-20UG
About this Product
SKU:
6382-MSM6-P0
Application:
Flow Cytometry, Immunohistochemistry
translate.label.attr.clone:
rSDC1/6866
Clonality:
Monoclonal
Extra Details:
CD138; also designated syndecan-1; is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells; while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining; except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms; CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinoma.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa200-300) of human CD138 protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
85kDa
Research Area:
Articular Cartilage Extracellular Matrix; B Cell Markers; Cytokine Signaling; Hematopoietic Stem Cells; Immunology; Infectious Disease; Mesenchymal Stem Cell Differentiation
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody