CEACAM1 (CEA Cell Adhesion Molecule 1) / CD66a Antibody
Product Sizes
100 ug
£671.00
634-MSM41-P1-100UG
About this Product
- SKU:
- 634-MSM41-P1
- Additional Names:
- Biliary glycoprotein 1
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- CEACAM1/12661
- Clonality:
- Monoclonal
- Extra Details:
- Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain; with structural homology to the immunoglobulin variable domains; followed by a variable number of immunoglobulin constantlike A and/or B domains. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1); also known as BGP or BGP1; is a 526 amino acid protein that exists as seven alternatively spliced isoforms; some of which localize to the cell membranes; while others are secreted. One of several members of the CEACAM family; CEACAM1 contains one Ig-like V-type domain and three Ig-like C2-type domains and is thought to play a role in a variety of cellular activities; including angiogenesis; apoptosis; arrangement of tissue threedimensional structure and modulation of innate and adaptive immune responses. Additionally; CEACAM1 is underexpressed in colorectal cancers; suggesting a role in tumor suppression.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-200) of human CEACAM1 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 90-180kDa
- Research Area:
- Hematopoietic Stem Cells; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=143087
