Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Recombinant S100B (Astrocyte and Melanoma Marker) Antibody

Product Sizes
100 ug
£671.00
6285-RBM42-P1-100UG
About this Product
SKU:
6285-RBM42-P1
Additional Names:
S-100 protein beta chain | S-100 protein subunit beta | S100 calcium-binding protein B
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
S100B/12587R
Clonality:
Monoclonal
Extra Details:
S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes; Langerhans cells; histiocytes; chondrocytes; lipocytes; skeletal and cardiac muscle; Schwann cells; epithelial and myoepithelial cells of the breast; salivary and sweat glands; as well as in glial cells. Neoplasms derived from these cells also express S-100 protein; albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland; adipose and cartilaginous tissue; and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
Host:
Rabbit
Immunogen:
Recombinant full-length human S100B protein
Isotype:
IgG
Molecular Weight:
10-12kDa
Research Area:
Cardiovascular; Cytokine Signaling; Dendritic Cell Marker; Immunology; Neural Stem Cells; Neuroscience; Nuclear Marker; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody