Calprotectin / MRP14 / S100A9 / Calgranulin B Antibody
Product Sizes
100 ug
£671.00
6280-MSM4-P1-100UG
About this Product
- SKU:
- 6280-MSM4-P1
- Additional Names:
- Calgranulin-B | Calprotectin L1H subunit | Leukocyte L1 complex heavy chain | Migration inhibitory factor-related protein 14 | S100 calcium-binding protein A9
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- CPT/1028
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes the L1 or Calprotectin molecule; an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain. Calprotectin comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes; macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly; neutrophils only intracellularly. Calprotectin has antibacterial; antifungal; immunomodulating and antiproliferative effects. Besides this it is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity; like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore calprotectin is also detectable in feces. Elevated levels of calprotectin have been observed in body fluids such as plasma; saliva; gingival crevicular fluid; stools; and synovial fluid during infection and inflammatory conditions.This MAb reacts with neutrophils; monocytes; macrophages; and squamous mucosal epithelia and is important for identifying macrophages in tissue sections.
- Host:
- Mouse
- Immunogen:
- Recombinant human Calprotectin protein
- Isotype:
- IgM
- Molecular Weight:
- 14kDa
- Research Area:
- Cardiovascular; Dendritic Cell Marker; Immunology; Infectious Disease; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120937
