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Antibodies

Calprotectin / MRP14 / S100A9 / Calgranulin B Antibody

Product Sizes
100 ug
£671.00
6280-MSM3-P1ABX-100UG
About this Product
SKU:
6280-MSM3-P1ABX
Additional Names:
Calgranulin-B | Calprotectin L1H subunit | Leukocyte L1 complex heavy chain | Migration inhibitory factor-related protein 14 | S100 calcium-binding protein A9
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry
translate.label.attr.clone:
MRP14/840
Clonality:
Monoclonal
Extra Details:
Recognizes a protein of14kDa; identified as MRP-14 (also known as Calgranulin B or S100AA9). It comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes; macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly; neutrophils only intracellularly. It is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity; like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore; it is also detectable in feces. Elevated levels have been observed in body fluids such as plasma; saliva; gingival crevicular fluid; stools; and synovial fluid during infection and inflammatory conditions. This MAb reacts with neutrophils; monocytes; and macrophages; and has been shown as an important marker for identifying macrophages in tissue sections.
Host:
Mouse
Immunogen:
Recombinant human MRP14 protein
Isotype:
IgM
Molecular Weight:
14kDa
Research Area:
Cardiovascular; Dendritic Cell Marker; Immunology; Infectious Disease; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody