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Antibodies

Calprotectin / MRP14 / S100A9 / Calgranulin B Antibody

Product Sizes
20 ug
£364.00
6280-MSM1-P0-20UG
About this Product
SKU:
6280-MSM1-P0
Additional Names:
Calgranulin-B | Calprotectin L1H subunit | Leukocyte L1 complex heavy chain | Migration inhibitory factor-related protein 14 | S100 calcium-binding protein A9
Application:
Immunohistochemistry
translate.label.attr.clone:
S100A9/1011
Clonality:
Monoclonal
Extra Details:
Recognizes a 14kDa protein; identified as S100A9 (also known as Calgranulin B or MRP-14); expressed by granulocytes; monocytes and by tissue macrophages.The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells; and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of this protein is associated with the disease cystic fibrosis. This MAb reacts with neutrophils; monocytes and macrophages; and has been shown as an important marker for identifying macrophages in tissue sections. Among cells that are now recognized as macrophages are histiocytes; Kupffer cells; osteoclasts; microglial cells; synovial type A cells; interdigitating cells; and Langerhans cells (in normal tissues) and epithelioid cells and Langerhans-type and foreign-body-type multinucleated giant cells (in inflamed tissues).
Host:
Mouse
Immunogen:
Recombinant human S100A9 protein
Isotype:
IgM
Molecular Weight:
14kDa
Research Area:
Cardiovascular; Dendritic Cell Marker; Immunology; Infectious Disease; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody