Recombinant S100A9 + Calprotectin (S100A8/A9 Complex) Antibody
Product Sizes
100 ug
£671.00
6279-RBM5-P1ABX-100UG
About this Product
- SKU:
- 6279-RBM5-P1ABX
- Additional Names:
- Calgranulin-A | Calprotectin L1L subunit | Cystic fibrosis antigen | Leukocyte L1 complex light chain | Migration inhibitory factor-related protein 8 | S100 calcium-binding protein A8 | Urinary stone protein band A
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MAC3157R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes the L1 or Calprotectin molecule; an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain expressed by granulocytes; monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues; the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes); liver (Kupffer's cells); lung (alveolar macrophages); lymph nodes (free and fixed macrophages); spleen (free and fixed macrophages); bone marrow (fixed macrophages); serous fluids (pleural and peritoneal macrophages); skin (histiocytes; Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system; recognizing; engulfing and destroying many potential pathogens including bacteria; pathogenic protozoa; fungi and helminthes. This MAb reacts with neutrophils; monocytes; macrophages; and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
- Host:
- Rabbit
- Immunogen:
- Affinity Purified monocyte membrane preparation
- Isotype:
- IgG
- Molecular Weight:
- 12-14kDa (doublet)
- Research Area:
- Immunology; Infectious Disease; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120933
