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Antibodies

Recombinant Ribonucleotide Reductase M1 / RRM1 Antibody

Product Sizes
100 ug
£671.00
6240-RBM1-P1ABX-100UG
About this Product
SKU:
6240-RBM1-P1ABX
Additional Names:
Ribonucleoside-diphosphate reductase subunit M1 | Ribonucleotide reductase large subunit
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
RRM1/4372R
Clonality:
Monoclonal
Extra Details:
Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase; an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis; tumor progression; and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to residues within aa700-800 of human RRM1 (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
94kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody