Recombinant ROS1 Antibody
Product Sizes
20 ug
£364.00
6098-RBM3-P0-20UG
About this Product
- SKU:
- 6098-RBM3-P0
- Additional Names:
- Proto-oncogene c-Ros | Proto-oncogene c-Ros-1 | Receptor tyrosine kinase c-ros oncogene 1 | c-Ros receptor tyrosine kinase
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- ROS1/7999R
- Clonality:
- Monoclonal
- Extra Details:
- ROS1; an orphan receptor tyrosine kinase of the insulin receptor family; was initially identified as a homolog of v-ros from the UR2 sarcoma virus. ROS1 consists of a large extracellular domain that is composed of six fibronectin repeats; a transmembrane domain; and an intracellular kinase domain. While the function of ROS1 is undefined; it has been shown to play an important role in differentiation of epididymal epithelium. The first oncogenic fusion of ROS1; FIG-ROS1; was initially identified by research studies in glioblastoma. Investigators have found additional oncogenic ROS1 fusion proteins in NSCLC (at a frequency of ~1.6%); where the ROS1 kinase domain is fused to the amino-terminal region of a number of different proteins; including CD74 and SLC34A2.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment corresponding to cytoplasmic domain of human ROS1 protein
- Isotype:
- IgG
- Molecular Weight:
- 264kDa
- Research Area:
- AKT Signaling
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=129314
