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Antibodies

Recombinant ROR-gamma / RORC (RAR-related Orphan Receptor C) Antibody

Product Sizes
20 ug
£364.00
6097-RBM9-P0-20UG
About this Product
SKU:
6097-RBM9-P0
Additional Names:
Nuclear receptor RZR-gamma | Nuclear receptor subfamily 1 group F member 3 | RAR-related orphan receptor C | Retinoid-related orphan receptor-gamma
Application:
Immunohistochemistry
translate.label.attr.clone:
RORC/8132R
Clonality:
Monoclonal
Extra Details:
Retina-associated orphan receptors (RORs) contains three subtypes: RORα; RORβ; and RORÎ �. They are widely distributed in body tissues; and most of them can directly enter the nucleus to regulate the transcription of target genes; thus showing different tissue specificity and participating in different physiological processes. In particular; RORα and RORÎ � play an important role in mediating Th17 cell differentiation. RORÎ � can be divided into RORÎ �1 and RORÎ �2 (RORÎ � T); which show different tissue specificity. ROR Gamma (T) is expressed only in lymphoid compartment cells; i.e.; CD4+CD8+ double positive thymocytes; peripheral Th17 cells; and lymphoid tissue inducer (LTi) cells of lymphoid organs. At present; RORÎ � T is considered as a new target for drug development against autoimmune diseases; especially psoriasis. In recent years; RORÎ � T small molecule inhibitors have become a hot research field in academia and even international pharmaceutical companies; with great development potential.
Host:
Rabbit
Immunogen:
Recombinant full-length human ROR gamma T protein
Isotype:
IgG
Molecular Weight:
55kDa
Research Area:
Cytokine Signaling; Immunology; Nuclear Marker; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody