Recombinant CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) Antibody
Product Sizes
100 ug
£671.00
608-RBM6-P1ABX-100UG
About this Product
- SKU:
- 608-RBM6-P1ABX
- Additional Names:
- B-cell maturation protein
- Application:
- ELISA, Immunohistochemistry
- translate.label.attr.clone:
- CD269/7986R
- Clonality:
- Monoclonal
- Extra Details:
- The B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML; which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1; which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed; TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).
- Host:
- Rabbit
- Immunogen:
- Recombinant human CD269 protein fragment (around aa 1-184) (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 20kDa
- Research Area:
- AKT Signaling; B Cell Markers; Cytokine Signaling; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=128347
