BACH2 (Transcription Factor) Antibody
Product Sizes
100 ug
£671.00
60468-MSM2-P1-100UG
About this Product
- SKU:
- 60468-MSM2-P1
- Additional Names:
- BTB and CNC homolog 2
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- PCRP-BACH2-5B11
- Clonality:
- Monoclonal
- Extra Details:
- Enables sequence-specific double-stranded DNA binding activity. Involved in primary adaptive immune response involving T cells and B cells. Located in cytosol and nucleoplasm. Implicated in immunodeficiency 60. Transcriptional regulator that acts as a repressor or activator. Binds to Maf recognition elements (MARE). Plays an important role in coordinating transcription activation and repression by MAFK. Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1. Positively regulates the nuclear import of actin. Is a key regulator of adaptive immunity; crucial for the maintenance of regulatory T-cell function and B-cell maturation.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa11-132) of human BACH2 protein
- Isotype:
- IgG2a
- Molecular Weight:
- 92.54kDa
- Research Area:
- B Cell Markers
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=139407
