RET Proto-oncogene Antibody
Product Sizes
20 ug
£364.00
5979-MSM11-P0-20UG
About this Product
- SKU:
- 5979-MSM11-P0
- Additional Names:
- Cadherin family member 12 | Proto-oncogene c-Ret
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- RET/8786
- Clonality:
- Monoclonal
- Extra Details:
- The Ret proto-oncogene is structurally related to the growing family of tyrosine kinase transmembrane receptors and is involved in GDNF signaling. RET expression is reported in several regions of the central nervous system; in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia; in motor neurons in the spinal cord and hindbrain; in neuro-retina and the growing tips of the renal collecting ducts in developing kidney.Alterations in RET ÔøΩgene are associated with diseases including papillary thyroid carcinoma; multiple endocrine neoplasia (type 2A and 2B); familial medullary thyroid carcinoma; and a congenital developmental disorder known as Hirschsprung s disease.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 702-848) of human RET protein (exact sequence is proprietary)
- Isotype:
- IgG2c
- Molecular Weight:
- 150kDa (precursor); 170kDa (Mature)
- Research Area:
- Developmental Biology; Neuroscience; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=131232
