NF-kB p65 / RELA Antibody
Product Sizes
100 ug
£671.00
5970-MSM2-P1-100UG
About this Product
- SKU:
- 5970-MSM2-P1
- Additional Names:
- Nuclear factor NF-kappa-B p65 subunit | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-RELA-2B6
- Clonality:
- Monoclonal
- Extra Details:
- Proteins encoded by the v-Rel viral oncogene and its cellular homolog; c-Rel; are members of a family of transcription factors that include the two subunits of the transcription factor N B (p50 and p65) and the Drosophila maternal morphogen; dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp B sequence in the immunoglobulin light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NF B is activated and NF B is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins of the same size have been described; designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule; designated pdI; binds to p50 and regulates its activity.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human RELA protein
- Isotype:
- IgG1
- Molecular Weight:
- 65kDa
- Research Area:
- Cardiovascular; Cytokine Signaling; Developmental Biology; Immunology; Infectious Disease; Lung Cancer; MAPK Signaling; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120695
