Recombinant Bcl-2 (Apoptosis & Follicular Lymphoma Marker) Antibody
Product Sizes
100 ug
£671.00
596-RBM15-P1-100UG
About this Product
- SKU:
- 596-RBM15-P1
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- BCL2/6426R
- Clonality:
- Monoclonal
- Extra Details:
- This antibody recognizes a protein of 25-26kDa; identified as the bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression ofbcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas; neoplastic germinal centers express high levels of bcl-2 lpha protein; whereas the normal or hyperplastic germinal centers are negative. Consequently; this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide; aa41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein
- Isotype:
- IgG
- Molecular Weight:
- 25-26kDa
- Research Area:
- AKT Signaling; Apoptosis; Autophagy; Basal Cell Marker; Cardiovascular; Cytokine Signaling; Immunology; Lung Cancer; Mitochondria Marker; Neuroinflammation; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120692
