Recombinant Bcl-2 (Apoptosis & Follicular Lymphoma Marker) Antibody

Product Sizes

20 ug

£364.00

596-RBM10-P0-20UG

About this Product

SKU:: 596-RBM10-P0
Application:: Immunohistochemistry, Western Blot
translate.label.attr.clone:: BCL2/2210R
Clonality:: Monoclonal
Extra Details:: This antibody recognizes a protein of 25-26kDa; identified as the bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas; neoplastic germinal centers express high levels of bcl-2 lpha protein; whereas the normal or hyperplastic germinal centers are negative. Consequently; this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
Host:: Rabbit
Immunogen:: Recombinant full-length human bcl-2 protein
Isotype:: IgG
Molecular Weight:: 25-26kDa
Research Area:: AKT Signaling; Apoptosis; Autophagy; Basal Cell Marker; Cancer; Cardiovascular; Cytokine Signaling; Hypoxia; Immunology; Lung Cancer; Mitochondria Marker; Neuroinflammation; Signal Transduction
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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