Recombinant RBP4 / Retinol Binding Protein 4 Antibody
Product Sizes
20 ug
£364.00
5950-RBM21-P0-20UG
About this Product
- SKU:
- 5950-RBM21-P0
- Additional Names:
- Plasma retinol-binding protein
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- RBP4/7045R
- Clonality:
- Monoclonal
- Extra Details:
- Retinol (Vitamin A) is transported in the blood bound to its carrier protein; retinol-binding protein (RBP); also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family; RBP conveys retinol from stores in the liver to peripheral tissues. In plasma; RBP binds transthyretin (TTR; formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP; resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein; recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa29-148) of human RBP4 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 25kDa
- Research Area:
- Cardiovascular; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120633
