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Antibodies

Recombinant ACE2 / Angiotensin | Converting Enzyme 2 Antibody

Product Sizes
20 ug
£431.00
59272-RBM7-P0-20UG
About this Product
SKU:
59272-RBM7-P0
Additional Names:
Angiotensin-converting enzyme homolog | Angiotensin-converting enzyme-related carboxypeptidase | Metalloprotease MPROT15
Application:
Immunohistochemistry
translate.label.attr.clone:
MSVA-919R
Clonality:
Monoclonal
Extra Details:
Carboxypeptidase which converts angiotensin I to angiotensin 1-9; a peptide of unknown function; and angiotensin II toangiotensin 1-7; a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage ofangiotensin II; may be an important regulator of heart function. By cleavage of angiotensin II; may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine; regulating trafficking; expression on the cell surface; and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections; serve as functional receptor for the spike glycoprotein of both coronaviruses.
Host:
Rabbit
Immunogen:
Recombinant fragment (around aa705-805) of human ACE2 (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
92kDa
Research Area:
Cardiovascular; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody