Rb1 (Tumor Suppressor Protein) Antibody
Product Sizes
20 ug
£364.00
5925-MSM1-P0-20UG
About this Product
- SKU:
- 5925-MSM1-P0
- Additional Names:
- p105-Rb | p110-RB1 | pRb | pp110
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- 1F8
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a 105kDa phosphoprotein; identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast; esophageal; squamous cell and cervical carcinoma.
- Host:
- Mouse
- Immunogen:
- Recombinant human Rb1 protein fragment of 283 amino acid residues.
- Isotype:
- IgG1
- Molecular Weight:
- 105kDa
- Research Area:
- Bladder Cancer; Breast Cancer; Cancer; Cardiovascular; Infectious Disease; Lung Cancer; Nuclear Marker; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120487
