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Antibodies

Recombinant Actin; Smooth Muscle (Leiomyosarcoma Marker) Antibody

Product Sizes
100 ug
£671.00
59-RBM7-P1ABX-100UG
About this Product
SKU:
59-RBM7-P1ABX
Additional Names:
Alpha-actin-2 | Cell growth-inhibiting gene 46 protein
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
ACTA2/13673R
Clonality:
Monoclonal
Extra Details:
Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This MAb does not stain cardiac or skeletal muscle; however; it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma; this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
Host:
Rabbit
Immunogen:
Recombinant fragment (around aa2-124) of human ACTA2 protein (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
42kDa
Research Area:
Cardiovascular; Mesenchymal Stem Cell Differentiation; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody