Ras-related C3 botulinum toxin substrate 1 Antibody
Product Sizes
100 ug
£671.00
5879-MSM1-P1-100UG
About this Product
- SKU:
- 5879-MSM1-P1
- Additional Names:
- Cell migration-inducing gene 5 protein | Ras-like protein TC25 | p21-Rac1
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- CPTC-RAC1-1
- Clonality:
- Monoclonal
- Extra Details:
- Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state; binds to a variety of effector proteins to regulate cellular responses such as secretory processes; phagocytosis of apoptotic cells; epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1; which is involved in stimulation of the NADPH oxidase activity in macrophages (By similarity). Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Rac1 has been demonstrated to play a critical role in tumor progression of human colorectal adenocarcinoma cells. In one study; overexpression of Rac1 accelerated the tumorigenic process; whereas Rac1 inhibition completed suppressed tumor formation.
- Host:
- Mouse
- Immunogen:
- Recombinant human full-length RAC1protein
- Isotype:
- IgG1
- Molecular Weight:
- 21kDa
- Research Area:
- BBB VCAM-1 Signaling; Cardiovascular; Developmental Biology; Immunology; Infectious Disease; MAPK Signaling; Nuclear Marker; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120453
