Recombinant CD45RA / LCA (B-Cell Marker) Antibody
Product Sizes
100 ug
£671.00
5788-RBM37-P1ABX-100UG
About this Product
- SKU:
- 5788-RBM37-P1ABX
- Additional Names:
- Leukocyte common antigen | T200
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- PTPRC/4367R
- Clonality:
- Monoclonal
- Extra Details:
- CD45 is a family of single chain transmembrane glycoproteins; consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are rod shaped; heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1q31-32.CD45 is exclusively expressed in haematolymphoid cells. Almost all haematolymphoid cells; including precursor cells and mature B- and T-lymphocytes; granulocytes; monocytes/histiocytes and interdigitating reticulum cells and follicular dendritic cells express CD45. This protein is detected in the large majority of haematolymphoid neoplasms; i.e.; leukemias and malignant lymphomas. Overall; about 90% of malignant lymphomas are CD45 positive.CD45 is an important marker in the primary tumor screening panel in order to identify haematolymphoid differentiation. Loss of CD45 in precursor B-cell neoplasms is a negative prognostic parameter.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa1-600) of human PTPRC protein (extracellular domain)
- Isotype:
- IgG
- Molecular Weight:
- 180-220kDa
- Research Area:
- B Cell Markers; Dendritic Cell Marker; Developmental Biology; Hematopoietic Stem Cells; Immunology; Mesenchymal Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=129313
