Recombinant CD45RA (Leucocyte Marker) Antibody
Product Sizes
100 ug
£671.00
5788-MSM32-P1ABX-100UG
About this Product
- SKU:
- 5788-MSM32-P1ABX
- Additional Names:
- Leukocyte common antigen | T200
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rPTPRC/1131
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 205kDa-220kDa; identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A; B and C; respectively. The differential splicing of the exons generates at least five isoforms; ABC; AB; BC; B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells; 50% of peripheral CD8+ T-cells; B-cells; and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary; predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human PTRPC protein
- Isotype:
- IgG1
- Molecular Weight:
- 205-220kDa
- Research Area:
- B Cell Markers; Dendritic Cell Marker; Developmental Biology; Hematopoietic Stem Cells; Immunology; Mesenchymal Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120334
