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Antibodies

26S proteasome non-ATPase regulatory subunit 4 Antibody

Product Sizes
100 ug
£671.00
5710-MSM1-P1ABX-100UG
About this Product
SKU:
5710-MSM1-P1ABX
Additional Names:
26S proteasome regulatory subunit RPN10 | 26S proteasome regulatory subunit S5A | Antisecretory factor 1 | Multiubiquitin chain-binding protein
Application:
Western Blot
translate.label.attr.clone:
CPTC-PSMD4-3
Clonality:
Monoclonal
Extra Details:
In eukaryotic cells; selective breakdown of cellular proteins is ensured by two distinct pathways. First; appropriate proteins are tagged for degradation by ubiquitination. Second; these multiubiquitinated proteins are degraded by the highly selective 26S Proteasome protein-destroying machinery. At specific stages of development; embryo- and tissue-specific components of the 26S Proteasome are formed; which are termed Rpn10a through Rpn10e; or alternatively pUb-R2 through pUb-R5. All members of this family can be generated by a single Rpn10 gene by developmentally regulated alternative splicing. The pUb-R2 subunit; originally identified as S5a (also designated antisecretory factor and multiubiquitin chain binding protein) is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. pUb-R4 and pUb-R5 may have embryo- or tissue-specific expression and may play specialized roles in early embryonic development.
Host:
Mouse
Immunogen:
Recombinant full-length human PSMD4protein
Isotype:
IgG2b
Molecular Weight:
~50kDa
Research Area:
Cytokine Signaling; Developmental Biology; Immunology; Infectious Disease; Nuclear Marker; Signal Transduction; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody