26S proteasome non-ATPase regulatory subunit 4 Antibody
Product Sizes
100 ug
£671.00
5710-MSM1-P1-100UG
About this Product
- SKU:
- 5710-MSM1-P1
- Additional Names:
- 26S proteasome regulatory subunit RPN10 | 26S proteasome regulatory subunit S5A | Antisecretory factor 1 | Multiubiquitin chain-binding protein
- Application:
- Western Blot
- translate.label.attr.clone:
- CPTC-PSMD4-3
- Clonality:
- Monoclonal
- Extra Details:
- In eukaryotic cells; selective breakdown of cellular proteins is ensured by two distinct pathways. First; appropriate proteins are tagged for degradation by ubiquitination. Second; these multiubiquitinated proteins are degraded by the highly selective 26S Proteasome protein-destroying machinery. At specific stages of development; embryo- and tissue-specific components of the 26S Proteasome are formed; which are termed Rpn10a through Rpn10e; or alternatively pUb-R2 through pUb-R5. All members of this family can be generated by a single Rpn10 gene by developmentally regulated alternative splicing. The pUb-R2 subunit; originally identified as S5a (also designated antisecretory factor and multiubiquitin chain binding protein) is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. pUb-R4 and pUb-R5 may have embryo- or tissue-specific expression and may play specialized roles in early embryonic development.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human PSMD4protein
- Isotype:
- IgG2b
- Molecular Weight:
- ~50kDa
- Research Area:
- Cytokine Signaling; Developmental Biology; Immunology; Infectious Disease; Nuclear Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120154
