Beta-2 Microglobulin (Renal Failure & Tumor Marker) Antibody
Product Sizes
20 ug
£364.00
567-MSM5-P0-20UG
About this Product
- SKU:
- 567-MSM5-P0
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- B2M/961
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 12kDa; identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1; alpha2; alpha3) and a non-covalent associating light chain; known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
- Host:
- Mouse
- Immunogen:
- Full length recombinant human B2M protein
- Isotype:
- IgG2b
- Molecular Weight:
- 12kDa
- Research Area:
- Cardiovascular; Cytokine Signaling; Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120095
