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Antibodies

MUC13 / Mucin 13 Antibody

Product Sizes
20 ug
£364.00
56667-MSM2-P0-20UG
About this Product
SKU:
56667-MSM2-P0
Additional Names:
Mucin-13; MUC-13; Down-regulated in colon cancer 1; UNQ6194/PRO20221; MUC13; RECC; DRCC1
Application:
Immunohistochemistry
translate.label.attr.clone:
MUC13/13112
Clonality:
Monoclonal
Extra Details:
Mucins are epithelial glycoproteins with a high content of clustered oligosaccharides that are O-glycoside linked to tandem repeat peptides rich in threonine; serine and proline. Mucin 13 (MUC13); also designated downregulated in colon cancer 1 (DRCC1); is an epithelial and hemopoietic type I membrane protein that undergoes secretion and influences gastrointestinal mucosa levels. It is most abundant in epithelial tissues of the gastrointestinal and respiratory tracts; such as large intestine and trachea; followed by kidney; small intestine; appendix and stomach. Mucin 13 is a good differentiation marker for gastrointestinal mucosa and may also indicate certain gastric tumors. It localizes to the apical membrane of both columnar and goblet cells in the gastrointestinal tract; and within goblet cell thecae. Mucin 13 is a cleaved protein; and the b subunit; containing the cytoplasmic tail; can homodimerize.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa100-300) of human MUC13 protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
58kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody