Protein Kinase C iota / lambda / PRKCI Antibody
Product Sizes
20 ug
£364.00
5584-MSM1-P0-20UG
About this Product
- SKU:
- 5584-MSM1-P0
- Additional Names:
- Atypical protein kinase C-lambda/iota | nPKC-iota
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- PRKCI/4911
- Clonality:
- Monoclonal
- Extra Details:
- Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions; including cell growth and differentiation; gene expression; hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes; including conventional (c) PKC isoforms (伪; 尾I; 尾II and 纬) and novel (n) PKC isoforms ( �L; ; �梅; ; ; l/i; m and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance; the kinase activities of PKC �L and are independent of Ca2+. On the other hand; most of the other PKC members possess phorbol ester-binding activities and kinase activities.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa100-300) of human PRKCI protein (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 68kDa
- Research Area:
- Cardiovascular; Complement System; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=120001
