UACA / Nucling (Nuclear Membrane Marker) Antibody
Product Sizes
20 ug
£364.00
55075-MSM1-P0-20UG
About this Product
- SKU:
- 55075-MSM1-P0
- Additional Names:
- UACA
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- AE-5
- Clonality:
- Monoclonal
- Extra Details:
- UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1;416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis; a characteristic of Vogt-Koyanagi-Harada disease; and in patients with Graves' disease. UACA was also later identified as Nucling; an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
- Host:
- Mouse
- Immunogen:
- Nuclei of myeloid leukemia biopsy cells
- Isotype:
- IgG1
- Molecular Weight:
- 160kDa
- Research Area:
- Apoptosis; Breast Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=119852
