PPARD Antibody
Product Sizes
100 ug
£671.00
5467-MSM6-P1-100UG
About this Product
- SKU:
- 5467-MSM6-P1
- Additional Names:
- NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | Peroxisome proliferator-activated receptor beta
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- PCRP-PPARD-4C2
- Clonality:
- Monoclonal
- Extra Details:
- Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that can be activated by a variety of compounds including fibratus; thiazolidinediones; prostaglandins and fatty acids. Three PPAR subtypes; designated PPARa; PPARb (also designated PPARÎ �) and PPARg; have been described. PPARs promote transcription by forming heterodimers with members of the retinoid X receptor (RXR) family of steroid receptors and binding to specific DNA motifs termed PPAR-response elements (PPREs). PPARa is abundant in primary hepatocytes; where it regulates the expression of proteins involved in fatty acid metabolism. PPARb is the most widely distributed subtype and is often expressed at high levels. PPARg is predominantly seen in adipose tissue; where it plays a critical role in regulating adipocyte differentiation. Interestingly; both the orphan nuclear hormone receptor LXRa and thyroid receptor (TR) have been shown to act as antagonists of PPARa/ RXRa binding to PPREs.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around 72-146) of human PPARD protein
- Isotype:
- IgG2a
- Molecular Weight:
- 49.9kDa
- Research Area:
- Cardiovascular; Endothelial Cell Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=131205
