EGLN1 / PHD2 Antibody
Product Sizes
100 ug
£671.00
54583-MSM1-P1ABX-100UG
About this Product
- SKU:
- 54583-MSM1-P1ABX
- Additional Names:
- Hypoxia-inducible factor prolyl hydroxylase 2 | Prolyl hydroxylase domain-containing protein 2 | SM-20
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- 366G/76/3
- Clonality:
- Monoclonal
- Extra Details:
- 366G/76/3 recognises human prolyl hydroxylase 2 (PHD2); a 46kDa enzyme expressed abundantly in all tissues with the highest expression in testis. Hypoxia inducible factor-1 (HIF-1) is a transcriptional complex; consisting of an alpha and beta subunit; which plays a key role in coordinating the cellular response to hypoxia. During normal oxygen conditions; the alpha subunit of HIF-1 is rapidly degraded; however when hypoxia occurs this degradation is suppressed and HIF-1 activates the transcription of various genes important for survival and adaptation to hypoxia. Prolyl hydroxylase 2 catalyses the hydroxylation of specific prolyl residues within the HIF-1 alpha subunit; thereby targeting this subunit for degradation.
- Host:
- Mouse
- Immunogen:
- Residues 1-24 of PHD2
- Isotype:
- IgG1
- Molecular Weight:
- 46kDa
- Research Area:
- Angiogenesis; Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=119767
