Recombinant OCT-2 (POU2F2) (B-Cell Marker) Antibody
Product Sizes
100 ug
£671.00
5452-RBM5-P1ABX-100UG
About this Product
- SKU:
- 5452-RBM5-P1ABX
- Additional Names:
- Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 | Octamer-binding protein 2 | Octamer-binding transcription factor 2
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- OCT2/7073R
- Clonality:
- Monoclonal
- Extra Details:
- Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites; regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells; mantle B-cells; monocytoid B-cells; and plasma cells show high level expression of Oct-2. Additionally; mantle cell lymphoma; follicular lymphoma; marginal zone lymphoma; plasmacytoma; Burkitt lymphoma; diffuse large cell lymphoma; diffuse large B-cell lymphoma; Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B; T-cell; myelomonocytic; and epithelial cell lines; whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells; it is believed that this factor participates in transcriptional regulation during T-cell activation.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 60kDa
- Research Area:
- Nuclear Marker; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=119766
