PON1 / Paraoxonase 1 Antibody
Product Sizes
100 ug
£671.00
5444-MSM1-P1-100UG
About this Product
- SKU:
- 5444-MSM1-P1
- Additional Names:
- Aromatic esterase 1 | K-45 | Serum aryldialkylphosphatase 1
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- PON1/1351
- Clonality:
- Monoclonal
- Extra Details:
- Paroxon is an organophosphorus anticholinesterase compound; used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution; inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1; which is expressed mainly in the liver; PON2 is expressed in a variety of mouse tissues; including the pancreas. PON3 is a associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-200) of human PON1 protein (exact sequence is proprietary)
- Isotype:
- IgG2
- Molecular Weight:
- 43kDa
- Research Area:
- Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=131178
