POLE3 / CHRAC17 Antibody
Product Sizes
20 ug
£364.00
54107-MSM2-P0-20UG
About this Product
- SKU:
- 54107-MSM2-P0
- Additional Names:
- Arsenic-transactivated protein | Chromatin accessibility complex 17 kDa protein | DNA polymerase II subunit 3 | DNA polymerase epsilon subunit p17
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- PCRP-POLE3-2F10
- Clonality:
- Monoclonal
- Extra Details:
- DNA replication is initiated by the binding of initiation factors to the origin of replication. Nucleosomes inhibit access to the replication machinery at these origin sequences. Nucleosome remodeling factors increase the accessibility of nucleosomal DNA to transcriptional regulators. CHRAC15 and CHRAC17 are subunits of the nucleosomal remodeling factor CHRAC (chromatin accessibility complex); which increases the accessibility of nucleosomal DNA in an ATP-dependent manner. Unlike other known chromatin remodeling factors; CHRAC also functions during chromatin assembly by using ATP to convert irregular chromatin into a regular array of nucleosomes with even spacing. This conversion process occurs when CHRAC organizes randomly deposited histones into a regularly spaced array. In the presence of CHRAC; the nucleosomal ATPase ISWI catalyzes several ATP-dependent transitions of chromatin structure.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human POLE3 protein
- Isotype:
- IgG1
- Molecular Weight:
- 16.86kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=119554
