IL20RA (Interleukin 20 Receptor Subunit Alpha) Antibody
Product Sizes
20 ug
£364.00
53832-MSM1-P0-20UG
About this Product
- SKU:
- 53832-MSM1-P0
- Additional Names:
- Cytokine receptor class-II member 8 | Cytokine receptor family 2 member 8 | IL-20R1 | ZcytoR7
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- IL20RA/0001
- Clonality:
- Monoclonal
- Extra Details:
- The class II cytokine receptor family includes 12 members; 11 of which combine as various heterodimers to transduce signals across the cellular membrane for 27 cytokines. These cytokines are divided into four structurally related groups: six cytokines of the IL-10 family; 17 type I IFNs; one type II IFN and three IFN-l. IL-20 is a member of the IL-10 family of cytokines that has been shown to be upregulated in psoriatic skin. The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ra and IL-20Rb. IL-20R also functions as a receptor for IL-19; IL-24 and IL-26. It is highly expressed in skin; brain and testis. IL-20; IL-20Ra and IL-20Rb all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin; suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-200) of human IL20RA protein (exact sequence is proprietary)
- Isotype:
- IgG2
- Molecular Weight:
- 90-100kDa
- Research Area:
- AKT Signaling; Cytokine Signaling; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=131633
