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Antibodies

PLK1 Antibody

Product Sizes
100 ug
£671.00
5347-MSM2-P1-100UG
About this Product
SKU:
5347-MSM2-P1
Additional Names:
Polo-like kinase 1 | Serine/threonine-protein kinase 13
Application:
ELISA, Immunohistochemistry
translate.label.attr.clone:
PLK1/7122
Clonality:
Monoclonal
Extra Details:
Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5; genes that are required for passage through mitosis in Drosophila and Saccharomyces; respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle; Plk protein content and catalytic activity peak at the onset of mitosis; followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta; as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.
Host:
Mouse
Immunogen:
Recombinant fragment of human PLK1 protein (around aa 1-200) (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
66kDa
Research Area:
Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody