BCL11A / CTIP1 (Transcription Factor) Antibody
Product Sizes
20 ug
£364.00
53335-MSM2-P0-20UG
About this Product
- SKU:
- 53335-MSM2-P0
- Additional Names:
- B-cell CLL/lymphoma 11A | COUP-TF-interacting protein 1 | Ecotropic viral integration site 9 protein homolog | Zinc finger protein 856
- Application:
- ELISA, Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-BCL11A-1H3
- Clonality:
- Monoclonal
- Extra Details:
- Bcl-11a (CtIP-1; EVI9; B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2; RIT1; B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia; and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia; and may function as a leukemia disease gene; in part; through its interaction with Bcl-6.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human BCLL1A protein
- Isotype:
- IgG1
- Molecular Weight:
- 91.2kDa
- Research Area:
- B Cell Markers; Cardiovascular; Infectious Disease; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=119522
