Prohibitin (Mitochondrial Marker) Antibody
Product Sizes
100 ug
£671.00
5245-MSM9-P1ABX-100UG
About this Product
- SKU:
- 5245-MSM9-P1ABX
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- PHB/3229
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 30kDa which is identified as Prohibitin; an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle; maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. Prohibitin is an ideal mitochondrial marker. It shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation; replicative senescence; cellular immortalization; and tumor suppression.
- Host:
- Mouse
- Immunogen:
- Recombinant human PHB protein fragment (aa167-261) (exact sequence is proprietary)
- Isotype:
- IgG2a
- Molecular Weight:
- 30kDa
- Research Area:
- Cardiovascular; Infectious Disease; Mitochondria Marker; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=119463
