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Antibodies

Progesterone Receptor (Marker of Progestin Dependence) Antibody

Product Sizes
20 ug
£364.00
5241-MSM7-P0-20UG
About this Product
SKU:
5241-MSM7-P0
Additional Names:
Nuclear receptor subfamily 3 group C member 3
Application:
Immunohistochemistry
translate.label.attr.clone:
PGR/3817
Clonality:
Monoclonal
Extra Details:
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms; PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect an intact estrogen regulatory machinery and therefore; predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa 483-571) of human PGR (exact sequence is proprietary)
Isotype:
IgG2b
Molecular Weight:
PR-A (81kDa) and PR-B (116kDa).
Research Area:
Breast Cancer; Cardiovascular; Signal Transduction; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody