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Antibodies

Recombinant CD31 / PECAM-1 (Endothelial Cell Marker) Antibody

Product Sizes
20 ug
£364.00
5175-RBM40-P0-20UG
About this Product
SKU:
5175-RBM40-P0
Additional Names:
EndoCAM | GPIIA' | PECA1
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
C31/8242R
Clonality:
Monoclonal
Extra Details:
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal; benign; and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis; and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Host:
Rabbit
Immunogen:
Recombinant fragment (aa 28-330) of human CD31 expressed in E. Coli (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
~100kDa (endothelium) and ~130kDa (platelets) �
Research Area:
Angiogenesis; Cardiovascular; Endothelial Cell Marker; Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody