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Antibodies

PDCD1 / PD1 / CD279 (Programmed Cell Death 1) Antibody

Product Sizes
100 ug
£671.00
5133-MSM2-P1-100UG
About this Product
SKU:
5133-MSM2-P1
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry
translate.label.attr.clone:
NAT105
Clonality:
Monoclonal
Extra Details:
PDCD-1 (programmed cell death-1 protein); also designated CD279; is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells; B-cells; and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6; PDCD-1 is expressed by few B-cells; so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition; PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
Host:
Mouse
Immunogen:
TY cells (human T/NK cell Leukemia)
Isotype:
IgG1
Molecular Weight:
55kDa
Research Area:
B Cell Markers; Cardiovascular; Immuno Oncology; Immunology; Infectious Disease; PD-1 blockade immunotherapy
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody