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Antibodies

Recombinant Claudin18.2 Antibody

Product Sizes
20 ug
£364.00
51208-RBM5-P0-20UG
About this Product
SKU:
51208-RBM5-P0
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
CLDN18.2/8559R
Clonality:
Monoclonal
Extra Details:
The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions; including the claudins; occludin and junction adhesion molecule. Claudins; which consist of four transmembrane domains and two extracellular loops; make up tight junction strands. Emerging evidence suggests that the claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.
Host:
Rabbit
Immunogen:
Recombinant fragment (around aa1-100) of human Claudin18.2 protein (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
27.8kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody