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Antibodies

ZBTB7B Antibody

Product Sizes
100 ug
£671.00
51043-MSM2-P1ABX-100UG
About this Product
SKU:
51043-MSM2-P1ABX
Additional Names:
Krueppel-related zinc finger protein cKrox | T-helper-inducing POZ/Krueppel-like factor | Zinc finger and BTB domain-containing protein 15 | Zinc finger protein 67 homolog | Zinc finger protein 857B | Zinc finger protein Th-POK
Application:
Flow Cytometry, Immunofluorescence, Western Blot
translate.label.attr.clone:
PCRP-ZBTB7B-1F7
Clonality:
Monoclonal
Extra Details:
TH-POK (T-helper-inducing POZ/Kr ppel-like factor); also known as zinc finger protein 67 (ZFP67); zinc finger and BTB domain-containing protein 7B or Kr ppel-related zinc finger protein cKrox; is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus; TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically; the presence of TH-POK directs positively selected thymocytes to the CD4 lineage; whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes; such as COL1A1; COL1A2 and Fibronectin.
Host:
Mouse
Immunogen:
Recombinant full-length human ZBTB7B protein
Isotype:
IgG2b
Molecular Weight:
58/80kDa
Research Area:
Nuclear Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody