PAX4 Antibody
Product Sizes
20 ug
£364.00
5078-MSM3-P0-20UG
About this Product
- SKU:
- 5078-MSM3-P0
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- PAX4/7598
- Clonality:
- Monoclonal
- Extra Details:
- Pax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing β cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon; Insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets; and the islet β cell lines MIN6; β TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80% identical to the deduced mouse Pax-4 protein.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-200) of human PAX4 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 38kDa
- Research Area:
- Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=130998
