PAX3 Antibody
Product Sizes
20 ug
£364.00
5077-MSM4-P0-20UG
About this Product
- SKU:
- 5077-MSM4-P0
- Additional Names:
- HuP2
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- PAX3/8424
- Clonality:
- Monoclonal
- Extra Details:
- Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis; Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain; midbrain and diencephalon. In 10-12 day embryos; expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia; the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes; encoding transcription factors; are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII; respectively.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa150-350) of human PAX3 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 56kDa
- Research Area:
- Cardiovascular; Mesenchymal Stem Cell Differentiation; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=138676
