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Antibodies

PAX3 Antibody

Product Sizes
100 ug
£671.00
5077-MSM1-P1ABX-100UG
About this Product
SKU:
5077-MSM1-P1ABX
Additional Names:
HuP2
Application:
ELISA
translate.label.attr.clone:
PAX3/4700
Clonality:
Monoclonal
Extra Details:
Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis; Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain; midbrain and diencephalon. In 10-12 day embryos; expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia; the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes; encoding transcription factors; are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII; respectively.
Host:
Mouse
Immunogen:
Synthetic peptide (quail) from the C-terminus
Isotype:
IgG2a
Molecular Weight:
56kDa
Research Area:
Cardiovascular; Mesenchymal Stem Cell Differentiation; Nuclear Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody