Recombinant PAX2 (Renal Cell & Ovarian Carcinoma Marker) Antibody
Product Sizes
100 ug
£671.00
5076-RBM13-P1ABX-100UG
About this Product
- SKU:
- 5076-RBM13-P1ABX
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- PAX2/8671R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 42kDa; which is identified as PAX2. It is a member of the paired box family of transcription factors; which is required for development and proliferation of the kidney; brain; and mullerian organs. PAX2 genes contain a highly conserved DNA sequence within the paired box region; which encodes a DNA-binding domain; enabling PAX proteins to bind the promoters of specific genes to transcriptionally regulate their expression. PAX2 is specifically expressed in the developing central nervous system; eye; ear; and urogenital tract; and is essential for the development of these organs. In normal adult tissues PAX2 was mainly detected in the urogenital system; including kidney; ureteric epithelium; fallopian tube epithelium; ovary and uterus. In tumors; PAX2 has been detected in renal cell carcinomas; Wilms' tumors; nephrogenic adenomas and papillary serous carcinoma of the ovary. PAX2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa 223-354) of human PAX2 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 42kDa
- Research Area:
- Neural Stem Cells; Nuclear Marker; Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=128816
