Recombinant Langerin / CD207 (Marker of Langerhans Cells) Antibody
Product Sizes
100 ug
£671.00
50489-RBM2-P1ABX-100UG
About this Product
- SKU:
- 50489-RBM2-P1ABX
- Additional Names:
- Langerin
- Application:
- ELISA
- translate.label.attr.clone:
- LGRN/3136R
- Clonality:
- Monoclonal
- Extra Details:
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent; C-type lectin domain containing; type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen; lymph node; thymus; liver; lung and heart express Langerin protein.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 48kDa
- Research Area:
- Dendritic Cell Marker; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=119043
